Grand Challenge: Biodiversity, evolution, and molecular mechanisms

Generating and harnessing fundamental knowledge of plants, their associated microbes, and their relationships with the environment

  • Gain insights into evolution and adaptation of plants and associated microbes
    • Define and model the evolutionary history and trajectory of plants across a broad range of spatiotemporal scales
    • Determine the developmental and environmental factors that drive adaptation of plants and plant-associated microbes
  • Characterize organismal and molecular diversity of plants and plant-associated microbes in natural and agricultural ecosystems
    • Elucidate processes underlying plant development, physiology, environmental responses and nutrition
    • Discover mechanisms governing plant-environment and plant-microbe interactions that include both beneficial and pathogenic microbes
    • Characterize and model the diverse relationships between plant systems, soil biogeochemistry and nutrient cycling, and their impact on climate
  • Translate complex plant and microbial systems to drive broadly beneficial biotechnological innovation
    • Leverage and integrate diverse data sets to model and predictively modulate biological processes
    • Bioengineer plants and their microbes with novel biological properties, and generate new plant-based products and synthetic communities (synthetic biology)

Research highlights: Biodiversity, evolution, and molecular mechanisms

Research spotlight: Biodiversity, evolution, and molecular mechanisms

How plants turn chaos into order

How does a plant reliably produce smooth leaves, protective flower parts and other complex structures? Adrienne Roeder is uncovering the cellular and molecular mechanisms that allow plants to grow with remarkable precision despite the inherent randomness of life.

A professor in Cornell's School of Integrative Plant Science, Roeder studies how groups of cells coordinate their behavior to shape developing plant organs. Her recent research revealed how cells can buffer noisy genetic signals and how differences in growth patterns and mechanical forces determine whether plant structures remain smooth or become wrinkled.

While driven by fundamental questions about how living organisms develop, these discoveries are laying the groundwork for future advances in crop improvement, synthetic biology and the engineering of living materials. By revealing the rules that govern plant form, Roeder's work helps explain how biological complexity emerges from individual cells.

Grand Challenge Research: Biodiversity, evolution, and molecular mechanisms

Tracking how plants respond to a changing world

From alpine mountaintops to island ecosystems, Hannah Marx studies how plant diversity evolves and how species adapt to changing environments over time. Her research combines fieldwork, evolutionary biology and genomic tools to better understand the forces that shape plant communities and their responses to environmental change, including climate change. 

As an assistant professor in the Plant Biology Section, Marx also directs the L.H. Bailey Hortorium Herbarium – one of North America's largest collections of preserved plants totalling roughly one million specimens. 

Herbarium collections serve as biological time capsules, providing historical records and genetic material that help researchers track shifting species distributions, changes in biodiversity and long-term ecological trends. Together, Marx's research and stewardship of the herbarium are helping scientists better understand and predict how plant ecosystems may change in the future.

Grand Challenge Research: Biodiversity, evolution, and molecular mechanisms

Teaching plants to communicate

When doctoral students Ava Forystek and Jacob Belding engineered tomato plants that turn vivid red when soil nitrogen runs low, they transformed a natural plant communication system into a tool for sustainable agriculture. Their innovation builds on the way plants sense nutrients through their roots and relay those signals to leaves and stems. 
 
By rewiring that molecular pathway to produce a visible red pigment, the students created a living sensor that could help growers identify nutrient deficiencies before crops become stressed, improving fertilizer efficiency while reducing nutrient runoff. 
 
The project demonstrates how discoveries in plant biology can be translated into practical solutions while deepening our understanding of the molecular mechanisms plants use to perceive and respond to their environment. The invention emerged from National Science Foundation’s Center for Research on Programmable Plant Systems (CROPPS), which fosters collaborations between scientists at Cornell and partner institutions.

Research spotlight: Biodiversity, evolution, and molecular mechanisms

Gene sequencing reveals healthier maize variants

While a staple in much of sub-Saharan Africa and Latin America, most maize varieties fall dangerously short in key nutrients like vitamin A and vitamin E.  Rather than engineer a solution in the lab, Michael Gore, professor in Plant Breeding and Genetics Section, turned to maize itself.  Over 15 years, Gore's lab "scanned thousands of maize varieties from around the globe. Using high-resolution mapping and advanced gene sequencing, they uncovered rare but powerful variants that naturally produce higher levels of beta-carotene, the precursor to vitamin A. Some of these maize lines, bright orange and brimming with nutrients, are now growing in Zambian fields through collaborations with HarvestPlus and CIMMYT," reports SeedWorld. “We didn’t need to invent a miracle,” Gore said. “We just had to listen to what maize already knew.”

Research spotlight: Biodiversity, evolution, and molecular mechanisms

Gene discovery may help growers battle grape downy mildew

Researchers at Cornell have discovered a new grape downy mildew resistance gene – giving the wine and grape industry a powerful new tool to combat this devastating disease. “Of the downy mildew resistance genes found in the world to date, this is one of the strongest,” said Lance Cadle-Davidson, adjunct professor in the School of Integrative Plant Science in the College of Agriculture and Life Sciences, and a research plant pathologist with the USDA’s Grape Genetics Research Unit in Geneva. “The discovery could help breeders develop more resistant grape varieties.”

Research spotlight: Biodiversity, evolution, and molecular mechanisms

Century-old mystery of plant communication solved

Imagine if a plant in a farmer’s field could warn a grower that it needs water? Or if a farmer could signal to plants that dry weather lies ahead. Margaret Frank, associate professor in the Plant Biology Section of the School of Integrative Plant Science, is one of the collaborators advancing our understanding of such two-way communication with plants through the efforts of the Center for Research on Programmable Plant Systems (CROPPS), which is funded by a five-year, $25 million National Science Foundation (NSF) grant.

 flower bud with wrinkled and irregular sepals
hannah marx with trowel above the treeline
students with tomato plants in greenhouse
michael gore with controller in corn field
downy mildew on grape stem
cropp graphic