Permit / halosulfuron
Chemical Name:
methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate
Chemical Family: Sulfonyl ureas
EPTC effects
EPTC (PPI) on winter wheat
Note abnormal growth of leaves from coleoptiles
EPTC effects
EPTC (PPI) on grasses
EPTC effects
EPTC (PPI) on soybean
EPTC effects
EPTC (PPI) on broadleaf and grass crops and weeds
WSSA Resistance Group: 2
Crop/non-crop registration: Field and seed corn, grain sorghum
Sensitive weeds: Annual BLW (broadleaf weeds): cocklebur, velvetleaf, ragweed, wild mustard, redroot pigweed, Venice mallow, yellow nutsedge.
Application method: POST- in corn, from spike stage to 10 leaf stage (typically before crop is 50-76 cm tall (20-30").
Absorption & Translocation: Following foliar absorption, halosulfuron is rapidly absorbed through the leaves and translocated via both xylem and phloem.
Mode of Action: Inhibition of acetolactate synthase.
Metabolic pathway inhibited: Inhibits acetolactate synthase (ALS), also called acetohydroxyacid synthase (AHAS), a key enzyme in the biosynthesis of the branched-chain amino acids isoleucine, lecucine, and valine.
Basis of Selectivity: Metabolized by tolerant species to non-phytotoxic compounds.
Symptoms: Growth of treated plants is inhibited within a few hours after application and susceptible weeds are no longer competitive with the crop;following growth inhibition, meristematic areas gradually become chlorotic and necrotic, followed by a general foliar chlorosis and necrosis with complete control typically occurring within 1-2 wks.
Residuality: Intermediate (1- 4 months).
Toxicity: Oral LD50 = >1287 mg/kg - slightly toxic.
Additional comments: When early POST treatments are used in corn, sequential applications may be required to control later weed flushes; following application to foliage, allow 30 days before grazing domestic livestock, harvesting forage, or harvesting silage; halosulfuron can be tank mixed with a number of grass herbicides (atrazine, dicamba, nicosulfuron) to increase the spectrum of control.