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  • Biological and Environmental Engineering

Imagine a daily pill that can help control diabetes using the body’s own insulin. John March, associate professor of biological and environmental engineering, and collaborators have achieved this feat in rats using an engineered probiotic. Their special strain of Lactobacillus produces a protein that triggers insulin release, and diabetic rats given a daily dose for three months had up to 30 percent lower blood glucose levels than untreated rats. The probiotic converted a fraction of the cells on the inside surface of the rats’ upper intestine—approximately 1 in 1,600—into insulin-pumping pancreatic mimics. The technology is being licensed to BioPancreate, a wholly-owned subsidiary of Cortendo AB, a biopharmaceutical company incorporated in Sweden and based in Radnor, Pa., which will refine the therapy for human use.

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News

April 22, 2026 Awards Graduate Field Administrator Joanna Alario received the Casey Moore Impact Award from the Cornell Graduate School. This award is given to a member of the administrative community who contributes to the advancement of access...
a woman holds a sheep in a show stance

Field Note

Jessica Waltemyer, New York State small ruminant extension specialist with Cornell PRO-LIVESTOCK, likes to joke that animals rule her life. “Personally and professionally, it’s animals all the time,” she said. “There’s no part of my life that...
  • Cornell Cooperative Extension
  • PRO-LIVESTOCK
  • Animal Science