Computational genetics; Functional genomics of plant interactions with plant pathogenic bacteria; Role of TAL effects in plant disease and applications for disease control and DNA targeting, including genome editing
Statistical topics ranging from the bootstrap and Monte Carlo methods, clustering, exact inference, mixed models, generalized linear models, applications of the saddlepoint and Laplace approximations and model fitting algorithms.
Computational biology; Computational genetics; Genetics of adaptation and domestication; Bioinformatics
Population genetics, bacterial genomics, human microbiome, systems biology
Functional genomic approaches to dissect complex traits in grasses, cassava, and wide range of other crops; focused on combining the basic science of the molecular basis of natural variation with applied breeding
My research interests are broadly in the epidemiology of zoonotic diseases, evidence-based medicine, and One-Health. Recently, I have been developing methods to improve antimicrobial resistance surveillance and track multidrug resistance. I use classical statistical methods, mathematical modeling, and machine learning to answer research questions.
Molecular and theoretical population genetics; molecular evolution; Drosophila evolutionary biology
Computational neuroscience, olfactory sensory processing, neural coding and representation; learning and memory systems, neuromorphic algorithms
Biomedical Sciences; gene regulation, functional genomic "next generation" sequencing data
Precision medicine; single-cell genomics; circulating cell-free DNA; genomic medicine
Biodiversity genomics; evolutionary biology; conservation genomics; population and quantitative genetics of birds
Plant disease sensing; asymptomatic disease detection; remote sensing; proximal sensing; in situ and imaging spectroscopy; machine & deep learning
Basic metabolism in ruminants and genetics to veterinary epidemiology, economic modeling and food safety
Computational ecology, behavior, and neurobiology; Collective behavior; Decision-making; Multi-scale modeling of biological systems; Data-driven modeling; Machine learning
Quantitative neuroimaging of neurological disorders, including multiple sclerosis, stroke, traumatic brain injury and disorders of consciousness
Epigenomic approaches to understanding the mechanisms of gene regulation in eukaryotic systems. We focus on combining genomics with bioinformatic algorithm development to deconvolute the eukaryotic regulatory network.
Neuroscience, neural coding, neuromodulation, olfactory sensory processing, and the neural bases of learning and memory processes
Gene expression, gene regulation, molecular biology, molecular genetics, Rna aptamers, Rna splicing, transcription
Population genetics, computational evolutionary biology, evolutionary theory, genetics of rapid adaptation
Quantitative genetics/genomics; statistical genetics; computational biology; pathway modeling; molecular evolution
Plant biology, evolutionary genomics, computational biology, metabolomics, natural product discovery
Systems biology, regulatory and signaling networks, biological information processing, and dynamics of complex systems
Computational approaches that investigate gene regulation in yeast and human epigenomes
Applying quantitative genetics, genomics and computational science to improve the efficiency of crop breeding programs and increase understanding of complex traits.
microRNA; gene regulation; genomics/bioinformatics; systems genetics; liver/GI stem cells; liver/GI disease; diabetes, dyslipidemia
Single cell multi'omics, computational genomics, systems biology, genomic medicine, cellular heterogeneity, tissue organization, kidney disease, cancer, Alzheimer's disease
Cancer genetics/genomics with a strong focus on the identification and functional characterization of novel predisposing mutations in human cancers.
Quantitative and experimental systems biology; statistical genetics; comparative genomics; machine learning; molecular evolution; disease prognosis analysis