I work in the laboratory of Yves Boisclair where we study hormonal regulation of metabolism using both in vivo and in vitro techniques. We utilize a variety of animal models including the dairy cow, sheep, and mice. I provide leadership in all phases of the research work performed by the laboratory: drafting protocols, designing, conducting and analyzing scientific experiments, and supporting the graduate and undergraduate lab members.
Education
Doctorate
Animal Science, Cornell University 2009
Master of Science
Animal Science, Cornell University 2004
Bachelor of Science
Animal Science, University of Idaho 2000
Recent Research
Ehrhardt, R.A., S.L. Giesy, S.M. Hileman, K.L. Houseknecht and Y.R. Boisclair. 2023. Effects of the central melanocortin system on feed intake, metabolic hormones and insulin action in the sheep. J. Anim. Sci 101:skad398. doi: 10.1093/jas/skad398.
McGuckin, M.M., S.L. Giesy, T.R. Overton and Y.R. Boisclair. 2023. Inflammatory tone in liver and adipose tissue in dairy cows experiencing a healthy transition from late pregnancy to early lactation. J. Dairy Sci 106:8122-8132. doi: 10.3168/jds.2023-23373
Lamb, C.L., S.L. Giesy, M. M. McGuckin, J. W. Perfield, 2nd, A. Butterfield, M. Moniruzzaman, N.J. Haughey, J. W. McFadden, and Y. R. Boisclair. 2022. Fibroblast growth factor-21 improves insulin action in nonlactating ewes. Am J Physiol Regul Integr Comp Physiol 322(3):R170-R180. doi: 10.1152/ajpregu.00259.2021
Ramos-Nieves, J. M., S. L. Giesy, M. M. McGuckin, and Y. R. Boisclair. 2020. Effects of birth weight and dietary fat on intake, body composition, and plasma thyroxine in neonatal lambs. J Anim Sci 98(12) doi: 10.1093/jas/skaa364
McGuckin, M. M., S. L. Giesy, A. N. Davis, M. A. Abyeta, E. A. Horst, S. Saed Samii, Y. Zang, W. R. Butler, L. H. Baumgard, J. W. McFadden, and Y. R. Boisclair. 2020. The acute phase protein orosomucoid 1 is upregulated in early lactation but does not trigger appetite-suppressing STAT3 signaling via the leptin receptor. J Dairy Sci 103(5):4765-4776. doi: 10.3168/jds.2019-18094
Caixeta, L. S., S. L. Giesy, C. S. Krumm, J. W. Perfield, 2nd, A. Butterfield, and Y. R. Boisclair. 2019. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. II. Pharmacokinetics, whole-animal performance, and lipid metabolism. J Dairy Sci 102(12):11597-11608. doi: 10.3168/jds.2019-16696
Krumm, C. S., S. L. Giesy, L. S. Caixeta, J. W. Perfield, 2nd, H. Sauerwein, B. L. Moore, and Y. R. Boisclair. 2019. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. I. Effects on signaling and indices of insulin action. J Dairy Sci 102(12):11586-11596. doi: 10.3168/jds.2019-16695
Ramos-Nieves, J. M., S. L. Giesy, W. S. Schwark, A. Gertler, and Y. R. Boisclair. 2019. Technical note: Effects of pegylation and route of administration on leptin kinetics in newborn lambs1. J Anim Sci 97(9):3768-3775. doi: 10.1093/jas/skz218
Rico, J. E., S. L. Giesy, N. J. Haughey, Y. R. Boisclair, and J. W. McFadden. 2018. Intravenous Triacylglycerol Infusion Promotes Ceramide Accumulation and Hepatic Steatosis in Dairy Cows. J Nutr 148(10):1529-1535. doi: 10.1093/jn/nxy155
Krumm, C. S., S. L. Giesy, C. L. Orndorff, and Y. R. Boisclair. 2018. Variation in x-box binding protein 1 (XBP1) expression and its dependent endoplasmic reticulum chaperones does not regulate adiponectin secretion in dairy cows. J Dairy Sci 101(6):5559-5570. doi: 10.3168/jds.2017-14048
