Andrew Grimson

• Doctorate 2004
  Department of Genetics, University of Wisconsin - Madison
• Bachelor of Arts 1997
  Department of Genetics, Trinity College Dublin (TCD)

My laboratory investigates post-transcriptional gene regulation. We have two areas of emphasis: first, the function of small RNA regulatory molecules (chiefly microRNAs), and second, the identification and characterization of novel cis-regulatory elements within mRNAs. These research areas represent my long-standing interest in the post-transcriptional regulation of mRNAs. As a graduate student, I investigated the NMD mRNA decay pathway, and as a postdoctoral fellow, I focused on miRNA target prediction and small RNA evolution. Our work typically combines high-throughput experimental and computational genomics, together with traditional experimental approaches. Ongoing projects include both fundamental studies in post-transcriptional regulation, for example: mechanistic characterization of novel regulatory pathways we have found; together with investigations into biological roles for post-transcriptional regulation, for example: investigating roles for small RNAs in the mammalian immune system.

• BIOMG 8369: Foundations and Frontiers in Cellular and Molecular Biology - I
• BIOG 4990: Independent Undergraduate Research in Biology
• BIOMG 7860: Research Seminar in Genetics and Development
• BIOMG 7870: Seminar in Genetics and Development