Priscila De Hora Vieira

My research is focused on understanding the molecular mechanisms underlying host-pathogen interactions. My goal is to investigate how infectious damage impacts the host immune response and cell turnover in the host intestinal epithelium. To address this, I have been working with one of the most relevant models that continues to impact human health worldwide—the insect vector Aedes aegypti. I apply a wide range of well-established molecular techniques and innovative omics science tools.

Before joining the Buchon Lab, my academic journey was primarily focused on understanding various cellular mechanisms such as endocytosis and autophagy during the vector/human cycle of neglected tropical diseases with global health importance, including Chagas, ZIKV, and DENV viruses, as well as insect physiology itself. As a postdoc, I began working on the development of new vaccine technologies using synthetic mRNAs. In this translational research project, I was involved in all stages of molecular and immunological assays, utilizing state-of-the-art technologies.

Altogether, my previous background and current research project will contribute to the scientific community's understanding of how the insect immune response is modulated by infection. It aims to elucidate the molecular mechanisms involved in stem cell activity, tissue homeostasis/repair and provide valuable knowledge that can be utilized as a strategy for disease control.